Chair for Drug Formulation and Delivery

    Marcus Gutmann

    Tel.: +49 931 31-88555

    E-Mail: marcus.gutmann[at]uni-wuerzburg.de

    Research Interests

    Marcus joined the group in June ’13. He works on the binding properties between bFGF and FGFBP and their role on different cell surface conditions. His field is the implementation of a FRET assay to show the central role the extracellular matrix and cell surface plays in proliferation and migration.

    Curriculum Vitae

    Studies of Pharmacy, University Regensburg

    Studies of Pharmacy, Ruprecht-Karls-University Heidelberg

    Practical Training, Pharmacy, Heidelberg

    Practical Training, Department of experimental pharmacology, University Mannheim

    License to practice Pharmacy

    Scientist, Dept. of Pharmacy and Food Chemistry, Chair of Pharmaceutics and Biopharmacy, University of Wuerzburg

    Publications / Posters

    Lühmann, T., Gutmann, M., et al. (2020). “Biodistribution of site-specifically PEGylated fibroblast growth factor-2.” ACS Biomater Sci Eng. 2020, 6, 1, 425-432, doi.org/10.1021/acsbiomaterials.9b01248. https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b01248

    Gutmann, M., Bechold, J., et al. (2019). “Metabolic glycoengineering of cell derived matrices and cell surfaces – a combination of key principles and step-to-step procedures.” ACS Biomater Sci Eng. 2019, 5, 1, pp.  215-233. https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.8b00865

    Reggane, M., Wiest, J., et al. (2018). "Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility." Eur J Pharm Biopharm. 2018 May 4, doi: 10.1016/j.ejpb.2018.05.012, [Epub ahead of print]. https://www.sciencedirect.com/science/article/pii/S0939641118304429

    Braun, A.C., Gutmann, M., et al. (2018). "Bioresponsive release of insulin-like growth factor-I from its PEGylated conjugate." J Control Release. 2018 Apr 7, doi: 10.1016/j.jconrel.2018.04.009, [Epub ahead of print]. https://www.sciencedirect.com/science/article/pii/S0168365918301913

    Gutmann, M., Braun, A., et al. (2018). "Bioorthogonal Modification of Cell Derived Matrices by Metabolic Glycoengineering." ACS Biomater Sci Eng. 2018 Mar 13, doi: 10.1021/acsbiomaterials.8b00264, [Epub ahead of print]. https://pubs.acs.org/doi/pdf/10.1021/acsbiomaterials.8b00264

    Braun, A.C., Gutmann, M., et al. (2018). "Bioorthogonal strategies for site-directed decoration of biomaterials with therapeutic proteins." J Control Release. 2018 Jan 19, doi: 10.1016/j.jconrel.2018.01.018, [Epub ahead of print]. https://www.ncbi.nlm.nih.gov/pubmed/29360478

    Griesbeck, S., Zhang, Z., et al. (2016). "Water-Soluble Triarylborane Chromophores for One- and Two-Photon Excited Fluorescence Imaging of Mitochondria in Cells." Chemistry. 2016 Oct 4, 22(41), pp. 14701-6. http://www.ncbi.nlm.nih.gov/pubmed/27627995

    Braun, A.C., Gutmann, M., et al. (2016). "Matrix Metalloproteinase Responsive Delivery of Myostatin Inhibitors." Pharm Res. 2017 Jan, 34(1), pp. 58-72. http://www.ncbi.nlm.nih.gov/pubmed/27628627

    Steiger, C., Uchiyama, K., et al. (2016). “Prevention of colitis by controlled oral drug delivery of carbon monoxide.” J Control Release. 2016 Oct 10, 239, pp. 128-136.     http://www.ncbi.nlm.nih.gov/pubmed/27578097 

    Dechnik, J., Mühlbach, F., et al. (2016). "Luminescent Metal–Organic Framework Mixed-Matrix Membranes from Lanthanide Metal–Organic Frameworks in Polysulfone and Matrimid." Eur. J. Inorg. Chem. 2016, 27, pp.4408-4415. www.onlinelibrary.wiley.com/doi/10.1002/ejic.201600235/abstract

    Gutmann, M., Memmel, E., et al. (2016). "Biocompatible Azide Alkyne"Click" Reactions for Surface Decoration of Glyco-Engineered Cells." Chembiochem. 2016 May 3, 17(9), pp. 866-75. www.ncbi.nlm.nih.gov/pubmed/26818821

    Lühmann, T., Jones, G., et al. (2015). "Bio-orthogonal Immobilization of Fibroblast Growth Factor 2 for Spatial Controlled Cell Proliferation." ACS Biomater Sci Eng 2015, 1(9), pp. 740-746. pubs.acs.org/doi/abs/10.1021/acsbiomaterials.5b00236

    Steiger, C., Wollborn, J., et al. (2015). “Controlled therapeutic gas delivery systems for quality-improved transplants.” Eur J Pharm Biopharm 2015, 97(A), pp. 96-106. www.sciencedirect.com/science/article/pii/S0939641115004245